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Healthcare

Farewell, Insulin? The Diabetes ‘Cartel’ Is Disrupting Itself, Proving Cynics Wrong

Diabetes affects nearly half a billion people worldwide, and the numbers are only going up with each generation. Recent research published by the American Diabetes Association and the CDC projects that by 2060 there will be at least 220,000 young people in the U.S. under the age of 20 with Type 2 diabetes. That’s a roughly 700 percent increase from just a few years ago. The disease poses one of the most significant known challenges to modern healthcare systems and has contributed to a new race for innovative, affordable solutions to weight gain and obesity. That race is led by Novo Nordisk, the maker of Ozempic and Wegovy, and it defies much of the usual cynicism about pharmaceutical giants. 

The impact of diabetes extends beyond individual suffering. It’s a condition with huge downstream economic effects – costing the United States a staggering $412 billion annually. Care for the condition accounts for about 10 percent of overall healthcare spending worldwide. As of 2023, people with diagnosed diabetes are responsible for one of every four dollars spent on healthcare in the U.S.

Insulin manufacturers frequently face criticism for escalating prices not making enough of the essential injections. Some U.S. states have even resorted to legal action, accusing insulin makers of maintaining artificial shortages. These companies are often vilified as the embodiment of greed, profiteers of patients’ misery.

U.S. Senator Bernie Sanders knocked Novo Nordisk at the end of March, saying “Novo Nordisk did the right thing by recently reducing the price of its insulin products by some 75% in America – a company that made nearly $15 billion in profits last year, must now do the right thing with respect to Ozempic and Wegovy.”

The world’s largest insulin producers, Eli Lilly and Novo Nordisk, are spearheading the transition to make insulin injections obsolete for millions with developments of drugs classified as glucagon-like peptide-1 receptor agonists (GLP-1) such as Mounjaro/Zepbound and Ozempic/Wegovy. Eli Lilly was the first to commercialize synthetic insulin in 1982 and these companies are now actively betting on disrupting their own business models which made them global leaders in pharmaceuticals. 

These drugs work by essentially mimicking certain hormones produced by the human body, boosting feelings of fullness and satiety.

Patients crave less food and have even shown shifts in their overall food preferences. People taking the drugs were shown pictures of foods and demonstrated “less desire for salty, spicy, high-fat, sweet, and savory foods.” This was also the case with starch and dairy. Eating healthier becomes so much easier on GLP-1 drugs.

Beyond weight loss, GLP-1 agonists reduce the risk of stroke and heart disease. They even might mitigate dementia and Parkinson’s. Recently, the FDA approved Wegovy for treating severe cardiovascular conditions. Some reports even suggest that these drugs moderate alcohol consumption and addictive behaviors like gambling.

Will these myriad benefits help alleviate healthcare inflation? Presently, GLP-1 agonists come at a considerable cost, with an annual treatment cycle averaging $12,000 per patient in the U.S. Growing competition could reduce the sticker shock. More importantly, patients whose long-term health is greatly bettered by the drugs will enjoy lower healthcare costs. 

Thus, GLP-1 agonists have the potential to trim healthcare costs by a few percentage points of GDP. If realized, that’s a very different, more healthy world. Sheila Kahyaoglu of Jefferies Financial told Bloomberg that United Airlines alone stood to save $80 million annually on fuel costs if the average passenger shed 5 kilograms of body weight. Meal delivery services and fast-food chains are rapidly adapting, offering healthier options to accommodate customers embracing healthier lifestyles.

Perhaps the most misguided and longstanding accusation about pharmaceutical companies is that they aim to profit from perpetual illness rather than pursue the creation of curative drugs. The industry disruption we’re witnessing around diabetes management and weight loss should long stand as a reminder of just how wrong that cynical claim is.

Originally published here

This Is Not the Time for a Shortage of Healthcare Workers

Winter is a busy time for impromptu hospital visits, whether from slipping on icy sidewalks or throwing out one’s back while shoveling snow. Then there’s the winter crud, which this year is particularly virulent. The CDC has reported that hospitalizations are up for influenza by 51 percent, 200 percent for COVID-19, and a 60 percent jump in RSV infections. Unfortunately, a shortage of nurses and other skilled healthcare workers could mean longer patient wait times.

The healthcare industry nationwide is in the thick of what is now termed the “Great Resignation.” Nearly half of American healthcare workers actively seek alternative employment opportunities, leaving patients with reduced access to healthcare providers and increased costs for services.

Because of this shortage of skilled healthcare workers, patients endure longer wait times in emergency rooms and urgent-care facilities and for crucial services like imaging, labs, exams, and routine or surgical procedures.

Patients deserve prompt access to quality care without delays in matters as critical as health and well-being. No one should have to endure long wait times at a medical facility.

We need more skilled healthcare workers throughout the United States. Still, we can’t sit on our hands and wait for the next generation of students to graduate and enter the workforce. Instead, America needs to tap into a global pool of skilled workers eager to contribute their talents immediately.

Unfortunately, bureaucratic hurdles in the form of visa labor caps exacerbate the labor deficit. Adding to the complexity is retrogression, a process that causes delays in visa processing as the annual visa limit approaches. These barriers make it increasingly difficult to fulfill America’s labor demand, ultimately leaving consumers feeling the pinch.

The crux of the issue lies in the caps and quotas imposed on employment-based visas for international skilled workers. These visa quotas have seen minimal adjustments to accommodate the modern economy, which has more than tripled in size since the quotas were created in 1990. The annual visa cap is set at 140,000, yet the unused employment-based visas reached 65,000 by the end of fiscal year 2021 due to processing capacity constraints. This problem has compounded, with 4.5 million unused employment-based visas since 1922.

The complexity of the system and the financial burdens associated with securing an employment-based visa add immensely to the challenges of entry. The complex application and approval process alone can take up to three years, and capacity constraints at Citizenship and Immigration Services create application backlogs and additional delays.

Countries such as the Philippines, with a significant population of nurses seeking to alleviate the healthcare shortage in the United States, experience lengthy wait times and high costs for their applications.

To address the repercussions patients face from labor shortages, the country must substantially increase the number of visas to at least 420,000 granted to skilled workers willing to help fill the gap. This move would be a boon for the healthcare industry and, most important, patients nationwide.

Unclaimed visas from previous years should be leveraged to bridge the gap quickly, ensuring that future labor shortages do not negatively affect American consumers. This would also help deter retrogression and eliminate unnecessary barriers. Politically, allowing unused visas to be rolled over and used to fill critical gaps could have bipartisan support. Economically, it alleviates labor market shortfalls and rewards migrants seeking to migrate via legal channels.

Patients need the gift of care. Policymakers have the power to give it by initiating visa labor cap reform. This would ensure that Americans spend less time in waiting rooms.

Originally published here

Health equity and trial diversity questions still not answered by pharma

While global players are more aware of health equity problems across the world, there are still lingering problems, according to Access to Medicine Foundation CEO Jayasree Iyer.

Speaking at the panel discussion ‘Health Equity – How Can Pharma Make a Difference?’ on the last day of the FT Global Pharma and Biotech Summit in London, UK, Iyer highlighted that commercial and access incentives need to be put together to improve health equity.

Seyda Atadan Memis, general manager of the UK and Ireland at Takeda, noted that while focusing on patients and building trust is crucial, it is also important to address affordability questions in each country.

Memis also said that health equity goes along with ethical considerations inside clinical trials. Takeda has translated its clinical trial guidelines into multiple languages for potential participants and caregivers to improve diversity and representation.

Clinical Trials Arena has previously reported on the importance of including patients from racially diverse backgrounds, improving female representation in early-stage studies, and the inclusion of the pregnant population and patients with cognitive disabilities.

Even though data plays a crucial role in the drug development process, it may also affect diversity. Liz Hampson, executive director of Europe at Deloitte Health Equity Institute, explained that biased data used to pick which products should enter clinical trials will influence what cohorts are enrolled into trials.

Read the full text here

Prestazioni sanitarie, tempi di attesa e nuove tecnologie

Presentato ieri un particolare ‘Indice di risparmio tempo’. I dati mettono a confronto i sistemi di dieci paesi sviluppati e ne evidenziano le disuguaglianze (allo scopo di correggere il sistema)

Il tempo è denaro, recita un vecchio adagio, ancor più se parliamo di quello che ciascuno di noi investe per la propria salute. Mentre la politica (e non solo) si interroga come abbattere le liste di attesa, il Consumer Choice Center (realtà consolidata che rappresenta i consumatori in oltre 100 Paesi del mondo) ha pubblicato un ‘indice di risparmio di tempo’. Di cosa si tratta? L’indice mette a confronto i sistemi di 10 Paesi sviluppati, tra i primi e gli ultimi classificati, in termini di tempo risparmiato dai pazienti per ottenere un appuntamento dal medico, andare in farmacia o in ospedale, ordinare i farmaci e accedere alla contraccezione.
Si tratta del primo database di questo tipo (o almeno con una ampia scala di valutazione), e si prefigge di offrire ai consumatori uno strumento utile a operare le scelte migliori e più sane per sé stessi, nonché di evidenziare lacune strutturali sulle quali richiamare l’attenzione delle politiche sanitarie dei singoli Paesi.

Read the full text here

#ConsumerChoice: Mental Health

At a time when NHS dental services are in crisis – and A&E, ambulance and nursing services are the focus of industrial action due to pay and conditions adding extra strain on the workload – protecting and supporting the mental health of staff in the workplace must become a priority.

A spokesperson from the Consumer Choice Center reports from an event in Switzerland that aims to address the situation.

As world leaders gather in Davos, Switzerland, the Consumer Choice Center hosted a panel on the importance of mental health support. Speakers discussed how challenges to mental health are increasing after the COVID-19 pandemic, the war in Ukraine, and economic uncertainty, and focused on effective coping techniques.

The “Prioritising Mental Health in Times of Global Crisis” panel was moderated by Jillian Melchior, editorial board member at The Wall Street Journal, with opening remarks by Kathleen Kingsbury, Opinion Editor at The New York Times.

Kingsbury told her audience: “Journalists are no strangers to stress, anxiety and trauma. Just last week we lost a reporter in the newsroom, Blake Hounshell, after a long battle with depression.

Read the full text here

Improving America’s Teeth

When was the last time you went to the dentist? If you’re now opening your calendar to check your last appointment, chances are it has been too long. There is no general rule on the regularity that will apply to all patients, not least because we all have different lifestyles. That said, if you are someone who consumes tobacco, drinks alcohol regularly, or if you are in doubt about whether your daily oral hygiene is up to standards, a good rule of thumb is to make a dentist appointment every six months.

For many Americans, the rudimentary costs of seeing a dentist for a routine checkup are manageable. Despite the fact that most dental plans cover 100% of the costs for preventive visits, many Americans appear to lack awareness of their benefits. Even though 80% Americans have access to dental benefits, nearly 35% of adults didn’t visit a dentist in 2019, according to the National Association of Dental Plans. For both the 20% of Americans who are either not employed or whose employer’s chosen insurance plan doesn’t cover dental care, and the existing insured patients, it would be important to increase competition through subscription models. My colleague Yaël Ossowski has explained the advantages of such subscriptions in the Boston Herald.

Improving America’s oral hygiene doesn’t just happen through the policy level of increasing competition or, as some argue, through getting the government more involved in the field of healthcare. First and foremost, oral hygiene happens at home through brushing and flossing. Unfortunately, that is where some Americans’ habits are falling short.

A 2021 study commissioned by the American Association of Endodontists showed that 21% of respondents failed to brush their teeth in the morning, 23% never floss, and 28% didn’t schedule a dental appointment the entire year. A 2016 analysis of 5,000 men and women had found that 32 percent of Americans never floss. This is all paired with headlines of less representative surveys showing that Americans mostly only brush once a day, if at all.

A factor that is underestimated by many is the effectiveness of chewing sugar-free gum. The American Dental Association says that while chewing sugar-free gum is no substitute for brushing your teeth, those gums sweetened by non-cavity-causing sweeteners such as aspartame, xylitol, sorbitol or mannitol can help prevent tooth decay. The saliva produced through chewing washes away food debris and neutralizes acids, and also carries with it more calcium and phosphate to help strengthen tooth enamel.

The European Food Safety Authority (EFSA), known for its cautious assessments of product claims, seconded the assessment that sugar-free gum improved tooth mineralization and thus has overall oral health benefits. It remains important to reiterate that sugar-free gum is in no way a substitute for regular oral hygiene; however, it is an adjunct to oral hygiene that makes it more than just a lifestyle but in fact, a wellness product.

Oral hygiene is an important factor in our daily lives. Tooth decay and lasting problems with teeth plague many Americans, burdening them with high dental costs. Both on a policy level and on an individual level, a lot remains to be done to improve the oral health of all citizens.

Originally published here

Oral health: household solutions for long-term benefits

As continuous lockdowns all over Europe require consumers to spend more time at home than ever before, many of them fall victim to complacency about exercise, and struggle to find focus in a working-from-home environment. Countless articles have already outlined tips for staying healthy while working in home offices. That said, there is a health tip consumers underestimate, and that is easier to put in practice than installing a Peloton next to your office desk: sugar-free gum.

The effects of sugar-free gum (SFG) have been analysed for a long time already. A 2011 study found that chewing gum reduces the desire for snacks by 10%, which makes a significant dent in cravings for those foods that are unhealthy. On top of the widely known added benefit of preventing tooth decay between regular dental hygiene, it has also been shown that chewing gum leads to increased cognitive performance and productivity. Given that consumers, as much as many others, currently spend their days on Zoom calls, chained to our desks, sugar-free gum has been one of many practical solutions that can help us snack less and be more focused. Sugar-free gum has also been mentioned as a tool for keeping anxiety induced by isolation during lockdowns at bay, and is prescribed by surgeons for post-surgery recovery.

Outside of the effect of staying more focused and not stuffing yourself with crisps, sugar-free gum also has benefits in the realm of oral hygiene and dental care. A recent King’s College London review analysed eight papers on the matter, in the attempt to answer the question: “What is the difference in the level of plaque quantity, in adults and children who chew sugar-free gum (SFG), compared with those who do not chew SFG, who do not chew gum or who use alternatives such as probiotics or fluoride varnish?” The review, published in a special edition of Frontiers in Oral Health & Preventive Dentistry, found evidence that SFG reduces dental caries. 2021 research data has previously indicated that Streptococcus mutans, which are a significant contributor to tooth decay, are reduced by chewing.

These evidence indicators have led the UK’s National Health Service1 to address SFG in its guidance on oral health. As evidence becomes more conclusive on the benefits of SFG, consumers should look out for the product as more than just a sugar-free candy replacement, but more as a practical health addition. This could have benefits not merely for individual oral health, but also to overall public health: research published in the British Dental Journal (BDJ) has shown that if 12-year-olds across the UK regularly chewed sugar-free gum after eating or drinking, it could save the NHS £8.2 million, the equivalent of 364,000 dental check-ups.


  1. specifically the Department of Health and Social Care, the Welsh Government, the Department of Health Northern Ireland, Public Health England, NHS England and NHS Improvement and with the support of the British Association for the Study of Community Dentistry.

Is Now the Time to Improve Canada’s Healthcare System?

Guest Host David Clement welcomes economist Ash Navabi and secondstreet.org President Colin Craig for an honest assessment of Canada’s fragile front line healthcare system and whether a private healthcare option might actually help.

Reckoning with insurance for better patient choice in healthcare

A new Senate bill seeks to take the hassle of dealing with healthcare companies away from patients and into the hands of insurance companies. Although it falls short of the mark, this bill is a step in the right direction toward sensible healthcare reform in Pennsylvania.

Regardless of your job, your income, or where you live, we’ve all had at least one nightmare scenario when it comes to health insurance.

There are forms, claims, reimbursement requests, schedules, and negotiations. Doctors, dentists, and health practitioners understand the burden, and often have to face their own bureaucratic tests of will before focusing on their patients. The growth of healthcare administration costs emphasizes this. And that’s for people with private plans.

The price inflation that comes with the amping up of health insurance plans in our entire system — not to mention the role of government subsidies — is a well-known phenomenon. Insurance becomes involved in every rudimentary doctor visit or procedure, leading to bad incentives for health providers, employers, and insurance companies. This process involves a middleman in what should essentially be a simple medical contract between patient and practitioner. 

The answer, however, is not in abandoning free exchange in healthcare, as Medicare For All proponents would have us believe, but rather it is in reckoning with insurance to make our system more competitive and fair.

In Pennsylvania, one particular bill is addressing the process of making insurance more accountable and lowering patient costs and headaches.

This session, State Sen. Judy Ward has introduced SB850 that would enact assignment of benefits reform, compelling insurance companies to follow a patient’s wish to directly pay healthcare providers rather than leaving them with the paperwork and negotiation. This would simplify life for patients by requiring insurers to pay providers directly.

One would think this is standard practice, but especially for dental insurance, there are additional steps and vetting that often leave patients responsible for paying their dentists only after the insurance company has paid out the claim.

Though only a small reform, and leagues from where we need to be to have a truly free market in healthcare decoupled from our employers, this bill would make the entire process simpler and better empower patients and consumers.

Since the Affordable Care Act and large Medicare reforms at the federal level, assignment of benefits is recognized in most medical insurance markets, but not yet for dental patients.

These reforms are complicated by the often cumbersome terms of dental insurance contracts: only portions of care or procedures can be covered by insurance, there are caps on the amounts one can reimburse in a single year, and dentists must navigate these steps to accurately bill their patients without producing a shocking bill. This balanced billing approach is necessary for any medical professional who wants to stay in business.

The answer, however, is not in abandoning free exchange in healthcare … but rather it is in reckoning with insurance to make our system more competitive and fair. 

But the status quo often makes it more complicated than it otherwise would be.

That is why price transparency remains an important principle for these debates, and why legislators should continue ensuring patients have choice and access to the information they need.

There are dozens of easy reforms state legislatures could follow that would help improve care: fostering innovation, reducing bureaucracy, giving incentives to patients to use direct-to-consumer options, and more.

By continuing to promote competition and transparency, patients and consumers can benefit from better care and lower costs. It is only a small degree of change we need, but it beats the alternative.

Originally published here

Simplify insurance for better health care

It is an unfortunate fact that most everyone has a health care insurance horror story.

In our overly complex and convoluted health care system, even routine checkups and minor appointments sometimes snowball into bureaucratic exercises of patience and will. While we thought health insurance would solve these issues, for some it has been made worse.

Whether at the primary care doctor, the dentist or the eye doctor, our reliance on insurance means that a simple transaction between patient and provider can often become complicated. For those without stellar plans, they must pay for care, then submit a claim to the insurer, negotiate the costs, wait for reimbursement and forward that payment to the provider. And that’s assuming the insurance company accepts the claim.

And while reform has been attempted at all levels of government, however well-intended, these have often served to further complicate the issues that come with being a patient in the American health care system, all the while giving more power to insurers.

At least one measure of progress can be found in a bill being pushed through the Pennsylvania Senate that would radically simplify the insurance process for dental patients.

State Sen. Judy Ward, R-Blair, and others have introduced a bill, SB850, that would enact what is known as assignment of benefits reform, requiring insurers to follow enrolled patients’ requests that the insurer directly pay a patient’s health care provider. There would be no additional forms, no additional waiting, and it would simplify the process so that patients could focus on getting what they need, rather than chasing an insurance claim.

This sounds intuitive, but at present, many dental insurance reimbursements must be vetted by the insurance company and then routed to the patients to pay their dentists. Not to mention any clauses found in insurance contracts that add additional steps.

If we were to simplify this process and empower patients, it would do wonders to improve care in this state — and perhaps free up at least one part of our health care system.

Critics of these reforms say they would put pressure on insurers, who would need to simplify and quickly pay health practitioners when patients tell them.

But conceding that point would mean allowing health insurers — who already have a dominant role in the health care industry — to complicate the process of reimbursing patients and providers with burdensome clauses and exemptions in their contracts.

After the Affordable Care Act and several Medicare reforms, assignment of benefits is a standard practice in general health care but so far does not exist across all medical categories. Passing this bill and getting it to Gov. Tom Wolf’s desk would be a strong measure of support for consumers and patients.

Of course, this level of legislation is far from the the large-scale reform needed. An eventual decoupling of insurance from dental and primary care for a more direct-to-consumer model altogether would be a radical way to improve our system, but this bill is a step in the right direction.

These laws have already been passed in states such as South Dakota, Colorado and West Virginia and are trending across the country, but more will be needed.

Indeed, there are plenty of easy reforms state legislatures could enact that would help improve care: fostering innovation, reducing bureaucracy, giving incentives to patients to use direct-to-consumer options and more.

Tax-saving accounts for education have been widely successful, and we could do more with health savings accounts even at a state level. Here, there is a role for government.

If we can continue to promote competition and transparency to provide better care, then patients and consumers will benefit. There are many patients and consumers with great plans that serve their needs. Nevertheless, there are still millions of Americans who want a better process.

Let us hope the Legislature understands this key point and helps make our health care easier, more affordable and pain-free.

Originally published here

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